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Sampath Kumar, K. P.
- Traditional Indian Herbal Plants Tulsi and Its Medicinal Importance
Authors
1 Department of Pharmaceutical Sciences, Coimbatore Medical College, Coimbatore, Tamilnadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 2 (2010), Pagination: 93-101Abstract
Tulsi has got the great medicinal value. Studies have also shown Tulsi to be effective for diabetes, by reducing blood glucose levels. The same study showed significant reduction in total cholesterol levels with Tulsi. Another study showed that Tulsi's beneficial effect on blood glucose levels is due to its antioxidant properties. The Rama Tulsi is the effective remedy for the severe acute Respiratory Syndrome. Juice of its leaves gives relief in cold, fever, bronchitis and cough. Tulsi oil is also used as the ear drop. Tulsi helps in curing malaria. It is very effective against indigestion, headache, hysteria, insomnia and cholera. The fresh leaves of Tulsi are taken by the millions of people every day. For over the centuries Tulsi (the queen of herbs) has been known for its remarkable healing properties. Modern scientific research offers impressive evidence that Tulsi reduces stress, enhances stamina, relieves inflammation, lowers cholesterol, eliminates toxins, protects against radiation, prevents gastric ulcers, lowers fevers, improves digestion and provides a rich supply of antioxidants and other nutrients. Tulsi is especially effective in supporting the heart, blood vessels, liver and lungs and also regulates blood pressure and blood sugar. Recent studies suggest that Tulsi may be a COX-2 inhibitor, like many modern painkillers, due to its high concentration of eugenol (1-hydroxy-2- methoxy-4-allylbenzene). Tulsi also shows some promise for protection from poisoning and cataracts. The oil extracted from the Karpoora Tulsi is mostly used in the herbal toiletry. Its oil is also used against the insects and bacteria. Tulsi can not only keep the dreaded Swine flu or H1N1 flu at bay but also help in fast recovery of an afflicted person, Ayurvedic practitioners claim. "The anti-flu property of Tulsi has been discovered by medical experts across the world quite recently. Tulsi improves the body's overall defence mechanism including its ability to fight viral diseases.- Zingiber officinale the Herbal and Traditional Medicine and Its Therapeutically Importance
Authors
1 Rajiv Gandhi College of Pharmacy Nautanwa, Maharajganj, Uttar Pradesh, IN
2 Department of Pharmaceutical Sciences, Coimbatore Medical Sciences, Coimbatore, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 2 (2010), Pagination: 102-110Abstract
Ginger is a perennial herb, with underground branching stems (rhizomes) which are swollen and tough. The leaves and rhizomes of ginger have a characteristic fragrance when cut or bruised. Rhizomes are dug out after the leafy parts are dried. Ginger, the underground stem, or rhizome, of the plant Zingiber officinale has been used as a medicine in Asian, Indian, and Arabic herbal traditions since ancient times. Ginger is considered an herbal remedy in many cultures. Over the years, it has been used to reduce inflammation, help with digestion, improve cardiovascular health and even historically to ward off diseases like the plague. The rhizome can be sliced, chopped, minced or served fresh but will always carry the trademark "heat" that has made it a medicinal mystery. Historically, people used ginger to fight disease and cure a fever since people would sweat when they would eat the ischolar_main. Although that helps, since it gets the metabolism racing and warms the body, we now realize that ginger offers additional medicinal benefits. Consumption of ginger helps with blood circulation and has antiinflammatory qualities that ease arthritis and other body aches and pains. It increases the body's production of saliva and other digestive fluids, which relieves an upset stomach and supports healthy digestion. Speeding up digestion helps clean the kidneys and bowels to remove toxins from the body. It also helps ease morning sickness, nausea and motion sickness. Ginger is said to improve digestion and has been known to pep up the appetite, promote saliva production, combat dyspepsia and relieve flatulent colic. It is also thought to be helpful for stomach cramps, alcoholic gastritis and hangover. The shogaol content in Ginger increases the activity of the digestive tract and is particularly helpful in digesting rich, fatty foods. Ginger has been used to cleanse the body of toxins through the skin by stimulating and increasing perspiration and has also been useful in breaking fevers. It is slightly diuretic and further cleanses the body by strengthening kidney function and increasing kidney filtration.
- Formulation and Evaluation of Telmisartan Fast Dissolving Tablets by Direct Compression Method
Authors
1 Himachal Institute of Pharmaceutical Education and Research, Nadaun, Hamirpur, H.P., IN
2 Department of Pharmacy, Coimbatore Government Medical College, Coimbatore, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 9, No 3 (2017), Pagination: 131-139Abstract
Telmisartan is a ACE inhibitor anti-hypertensive drug. Hence, in the present work, Telmisartan fast dissolving tablets will be prepared by using different super disintegrating agents. The amount of drug that is subject to first pass metabolism is reduced as compared to mouth dissolving tablets. Orally disintegration tablets contain wide variety of pharmaceutical active ingredients covering many therapeutic categories. The time for disintegration of orally disintegrating tablets are generally considered less than one minute. Orally disintegrating tablets are characterized by high porosity, low density and low hardness. The blend was examined for the precompressional parameters and post-compression parameters. Drug compatibility with excipients was checked by FTIR studies. The values of pre-compression parameters evaluated were within prescribed limits and indicated good free flowing property. In all the formulations, friability is less than 1%, indicated that tablets had a good mechanical resistance. Drug content was found to be in the range of 98 to 102%, which is within acceptable limits. Hardness of the tablets was found to be in the range of 3-4 Kp. The in vitro dispersion time was found to be in the range of 38-112sec with rapid in vitro dissolution within 3 min. No chemical interaction between drug and excipients was confirmed by FTIR studies. The drug release from tablets of Telmisartan prepared by direct compression showed that 98.20% drug release within 15 minutes.Keywords
Telmisartan, Fast Dissolving Tablets, Super Disintegrants.References
- Aulton M, Pharmaceutics, The Science Of Dosage Form Design, International student edition, published by Churchill Livingstone, 2002, 304-321.
- Ansel H, Allen L and Jr. Popovich N, Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems, 8th edition, published by Lippincott Williams and Wilkins, 2004, 227-259.
- Banker GS, Modern pharmaceutics, 3rd edition, Marcel Dekker Inc, New york, 2002, 576 – 820.
- Bi YX., Sunada, H., 25th edition, “Evaluation of rapidly disintegrating tablets prepared by Direct compression method”, Drug DevInd Pharm, 1999, 571-581.
- Chen, GL., Kuo MK., 52nd edition, “Formulation Design for Pioglitazone Rapid Release Tablet”, Chinese pharmaceutical Journal, 2000, 295-300.
- Chaudhari, PD., 42nd edition, “Formulation and evaluation of fast dissolving tablets of Famotidine”, Indian Drugs, 2005, 641649.
- Herbert A, Lieberman, Leon Lachman and Joseph B. Schwartz, Pharmaceutical Dosage Forms Tablets, 2003, 3rd edition, , 201238.
- Herbert A, Lieberman, Leon Lachman and Joseph B. Schwartz, Pharmaceutical Dosage Forms Tablets, 2003, 3rd edition, , 1-11.
- Hinz, B., Hug, AM., “Bioequivalence study of low-dose diclofenac potassium tablet formulations”, Int J Clin Phamacol Ther., 2009, 47th edition, 643-648.
- Jantratid E., “Reported the bio wavier Monographs for immediately release solid dosage forms cimetidine”, Journal of pharmaceutical Research, 2006, vol: 17, P: 381.
- Jacob Christensen and Vibeke Wallert Hamsen, Wet granulation in rotary processer and fluid bed: Comparison of granule and tablet properties, AAPS Pharma Sci Tech., Article22, 2006, 7th edition.
- Kuchekar B.S., Bhises S.B., Arumugam V. Indian J. Pharm. Educ. 2001, 150-152.
- Lachman L, Lieberman H and Kanig J, The Theory of practice of Industrial pharmacy, 3rdpublished by Lea and Febiger 1986, 346373.
- Larry Augsburger, L., Huijeoing Hahm, A., Albert Brezeczko, W., Umang shah Super disintegrants: Characterization and function, 2002, 2nd edition, 2623-2638.
- Mahajan, HS., Rapidly disintegrating tablets for elderly patients. The pharma Review, 8th edition, 2005, 49-52.